The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes

Induced pluripotent stem cells (iPSCs) have become a prevalent topic after their discovery, advertised as an ethical alternative to embryonic stem cells (ESCs). Due to their ability to differentiate into several kinds of cells, including cardiomyocytes, researchers quickly realized the potential for...

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Detalles Bibliográficos
Autores principales: Takahashi, Fuga, Patel, Praneel, Kitsuka, Takahiro, Arai, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952364/
https://www.ncbi.nlm.nih.gov/pubmed/36829731
http://dx.doi.org/10.3390/bioengineering10020237
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author Takahashi, Fuga
Patel, Praneel
Kitsuka, Takahiro
Arai, Kenichi
author_facet Takahashi, Fuga
Patel, Praneel
Kitsuka, Takahiro
Arai, Kenichi
author_sort Takahashi, Fuga
collection PubMed
description Induced pluripotent stem cells (iPSCs) have become a prevalent topic after their discovery, advertised as an ethical alternative to embryonic stem cells (ESCs). Due to their ability to differentiate into several kinds of cells, including cardiomyocytes, researchers quickly realized the potential for differentiated cardiomyocytes to be used in the treatment of heart failure, a research area with few alternatives. This paper discusses the differentiation process for human iPSC-derived cardiomyocytes and the possible applications of said cells while answering some questions regarding ethical issues.
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spelling pubmed-99523642023-02-25 The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes Takahashi, Fuga Patel, Praneel Kitsuka, Takahiro Arai, Kenichi Bioengineering (Basel) Review Induced pluripotent stem cells (iPSCs) have become a prevalent topic after their discovery, advertised as an ethical alternative to embryonic stem cells (ESCs). Due to their ability to differentiate into several kinds of cells, including cardiomyocytes, researchers quickly realized the potential for differentiated cardiomyocytes to be used in the treatment of heart failure, a research area with few alternatives. This paper discusses the differentiation process for human iPSC-derived cardiomyocytes and the possible applications of said cells while answering some questions regarding ethical issues. MDPI 2023-02-10 /pmc/articles/PMC9952364/ /pubmed/36829731 http://dx.doi.org/10.3390/bioengineering10020237 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Takahashi, Fuga
Patel, Praneel
Kitsuka, Takahiro
Arai, Kenichi
The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
title The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
title_full The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
title_fullStr The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
title_full_unstemmed The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
title_short The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
title_sort exciting realities and possibilities of ips-derived cardiomyocytes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952364/
https://www.ncbi.nlm.nih.gov/pubmed/36829731
http://dx.doi.org/10.3390/bioengineering10020237
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