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Shallow- and Deep-Water Ophiura Species Produce a Panel of Chlorin Compounds with Potent Photodynamic Anticancer Activities

A Pacific brittle star Ophiura sarsii has previously been shown to produce a chlorin (3S,4S)-14-Ethyl-9-(hydroxymethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid (ETPA) (1) with potent phototoxic activities, making it applicable to photodynamic therapy. Using extensive LC-MS metabolite p...

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Detalles Bibliográficos
Autores principales:	Klimenko, Antonina, Huber, Robin, Marcourt, Laurence, Tabakaev, Dmitry, Koval, Alexey, Dautov, Salim Sh., Dautova, Tatyana N., Wolfender, Jean-Luc, Thew, Rob, Khotimchenko, Yuri, Queiroz, Emerson Ferreira, Katanaev, Vladimir L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952619/ https://www.ncbi.nlm.nih.gov/pubmed/36829945 http://dx.doi.org/10.3390/antiox12020386

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