Pulmonary Pharmacokinetic and Pharmacodynamic Evaluation of Ampicillin/Sulbactam Regimens for Pneumonia Caused by Various Bacteria, including Acinetobacter baumannii

This study aimed to assess the dosing regimens of ampicillin/sulbactam for pneumonia based on pulmonary pharmacokinetic (PK)/pharmacodynamic (PD) target attainment. Using the literature data, we developed pulmonary PK models and estimated the probabilities of attaining PK/PD targets in lung tissue....

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Detalles Bibliográficos
Autores principales: Onita, Tetsushu, Ikawa, Kazuro, Ishihara, Noriyuki, Tamaki, Hiroki, Yano, Takahisa, Naora, Kohji, Morikawa, Norifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952633/
https://www.ncbi.nlm.nih.gov/pubmed/36830214
http://dx.doi.org/10.3390/antibiotics12020303

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