Stress Activated MAP Kinases and Cyclin-Dependent Kinase 5 Mediate Nuclear Translocation of Nrf2 via Hsp90α-Pin1-Dynein Motor Transport Machinery

Non-lethal low levels of oxidative stress leads to rapid activation of the transcription factor nuclear factor-E2-related factor 2 (Nrf2), which upregulates the expression of genes important for detoxification, glutathione synthesis, and defense against oxidative damage. Stress-activated MAP kinases...

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Detalles Bibliográficos
Autores principales: Ishii, Tetsuro, Warabi, Eiji, Mann, Giovanni E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952688/
https://www.ncbi.nlm.nih.gov/pubmed/36829834
http://dx.doi.org/10.3390/antiox12020274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952688/
https://www.ncbi.nlm.nih.gov/pubmed/36829834
http://dx.doi.org/10.3390/antiox12020274

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