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High-Throughput Screening for Epigenetic Compounds That Induce Human β-Defensin 1 Synthesis
Antimicrobial host defense peptides (HDPs) are critically important for innate immunity. Small-molecule compounds with the ability to induce HDP synthesis are being actively explored for antimicrobial therapy. To facilitate the discovery of the compounds that specifically activate human β-defensin 1...
Autores principales: | Lyu, Wentao, Deng, Zhuo, Zhang, Guolong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952773/ https://www.ncbi.nlm.nih.gov/pubmed/36830097 http://dx.doi.org/10.3390/antibiotics12020186 |
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