Cargando…
Acidosis Activates the Nrf2 Pathway in Renal Proximal Tubule-Derived Cells through a Crosstalk with Renal Fibroblasts
Crosstalk of renal epithelial cells with interstitial fibroblasts plays an important role in kidney pathophysiology. A previous study showed that crosstalk between renal epithelial cells and renal fibroblasts protects against acidosis-induced damage. In order to gain further mechanistic insight into...
Autores principales: | Schulz, Marie-Christin, Dubourg, Virginie, Nolze, Alexander, Kopf, Michael, Schwerdt, Gerald, Gekle, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952787/ https://www.ncbi.nlm.nih.gov/pubmed/36829971 http://dx.doi.org/10.3390/antiox12020412 |
Ejemplares similares
-
Epithelial–Fibroblast Crosstalk Protects against Acidosis-Induced Inflammatory and Fibrotic Alterations
por: Schulz, Marie-Christin, et al.
Publicado: (2022) -
Weighted Correlation Network Analysis Reveals CDK2 as a Regulator of a Ubiquitous Environmental Toxin-Induced Cell-Cycle Arrest
por: Dubourg, Virginie, et al.
Publicado: (2020) -
The nephrotoxin ochratoxin a impairs resilience of energy homeostasis of human proximal tubule cells
por: Schwerdt, Gerald, et al.
Publicado: (2023) -
The Impact of the Nephrotoxin Ochratoxin A on Human Renal Cells Studied by a Novel Co-Culture Model Is Influenced by the Presence of Fibroblasts
por: Schwerdt, Gerald, et al.
Publicado: (2021) -
Hypothesis-generating analysis of the impact of non-damaging metabolic acidosis on the transcriptome of different cell types: Integrated stress response (ISR) modulation as general transcriptomic reaction to non-respiratory acidic stress?
por: Dubourg, Virginie, et al.
Publicado: (2023)