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Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells

Polymyxins are last-line antibiotics for the treatment of Gram-negative ‘superbugs’. However, nephrotoxicity can occur in up to 60% of patients administered intravenous polymyxins. The mechanisms underpinning nephrotoxicity remain unclear. To understand polymyxin-induced nephrotoxicity, human renal...

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Detalles Bibliográficos
Autores principales:	Li, Mengyao, Azad, Mohammad A. K., Thompson, Philip E., Roberts, Kade D., Velkov, Tony, Zhu, Yan, Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952791/ https://www.ncbi.nlm.nih.gov/pubmed/36830325 http://dx.doi.org/10.3390/antibiotics12020415

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