Cargando…

The Regulatory Effect of Phytochemicals on Chronic Diseases by Targeting Nrf2-ARE Signaling Pathway

Redox balance is essential to maintain the body’s normal metabolism. Once disrupted, it may lead to various chronic diseases, such as diabetes, neurodegenerative diseases, cardiovascular diseases, inflammatory diseases, cancer, aging, etc. Oxidative stress can cause or aggravate a series of patholog...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Wen-Jiang, Lv, Cheng-Hao, Chen, Zhong, Shi, Meng, Zeng, Chao-Xi, Hou, De-Xing, Qin, Si
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952802/ https://www.ncbi.nlm.nih.gov/pubmed/36829795 http://dx.doi.org/10.3390/antiox12020236

Ejemplares similares

Phytochemical activators of Nrf2: a review of therapeutic strategies in diabetes: Phytochemical activators of Nrf2
por: Qin, Si, et al.
Publicado: (2022)

Targeting Nrf2 and NF-κB Signaling Pathways in Cancer Prevention: The Role of Apple Phytochemicals
por: Gado, Francesca, et al.
Publicado: (2023)

Regulatory Role of Nrf2 Signaling Pathway in Wound Healing Process
por: Süntar, Ipek, et al.
Publicado: (2021)

Nrf2–ARE Signaling Acts as Master Pathway for the Cellular Antioxidant Activity of Fisetin
por: Zhang, Huihui, et al.
Publicado: (2019)

Proanthocyanidins Activate Nrf2/ARE Signaling Pathway in Intestinal Epithelial Cells by Inhibiting the Ubiquitinated Degradation of Nrf2
por: Shuhua, Yang, et al.
Publicado: (2022)

Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
por: Bhattacharjee, Shamee, et al.
Publicado: (2020)

Crocetin Exerts Its Anti-inflammatory Property in LPS-Induced RAW264.7 Cells Potentially via Modulation on the Crosstalk between MEK1/JNK/NF-κB/iNOS Pathway and Nrf2/HO-1 Pathway
por: Wen, Yi-Ling, et al.
Publicado: (2021)

Dietary Phytochemicals Targeting Nrf2 to Enhance the Radiosensitivity of Cancer
por: Wang, Pinghan, et al.
Publicado: (2022)

Role of Phytochemicals in Skin Photoprotection via Regulation of Nrf2
por: Chaiprasongsuk, Anyamanee, et al.
Publicado: (2022)

Neuroprotection Against Oxidative Stress: Phytochemicals Targeting TrkB Signaling and the Nrf2-ARE Antioxidant System
por: Hannan, Md. Abdul, et al.
Publicado: (2020)

Phytochemical Combination PB125 Activates the Nrf2 Pathway and Induces Cellular Protection against Oxidative Injury
por: Hybertson, Brooks M., et al.
Publicado: (2019)

Downregulation of CIRP Prone Cells to Oxidative Injury via Regulating Nrf2 Signaling Pathway
por: Liu, Jing, et al.
Publicado: (2022)

Role of Oxidative Stress and Nrf2/KEAP1 Signaling in Colorectal Cancer: Mechanisms and Therapeutic Perspectives with Phytochemicals
por: Lee, Da-Young, et al.
Publicado: (2021)

Keap1/Nrf2 Signaling Pathway
por: Sykiotis, Gerasimos P.
Publicado: (2021)

Potential regulatory role of the Nrf2/HMGB1/TLR4/NF-κB signaling pathway in lupus nephritis
por: Li, Shi-jie, et al.
Publicado: (2023)

Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway
por: Xiang, Yukai, et al.
Publicado: (2018)

Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway
por: Su, Xuling, et al.
Publicado: (2018)

The Regulatory Roles of Polysaccharides and Ferroptosis-Related Phytochemicals in Liver Diseases
por: Ren, Yijing, et al.
Publicado: (2022)

Phytochemical and comparative transcriptome analyses reveal different regulatory mechanisms in the terpenoid biosynthesis pathways between Matricaria recutita L. and Chamaemelum nobile L.
por: Tai, Yuling, et al.
Publicado: (2020)

Discovery of Keap1−Nrf2 small−molecule inhibitors from phytochemicals based on molecular docking
por: Li, Maiquan, et al.
Publicado: (2019)

Sevoflurane preconditioning prevents acute renal injury caused by ischemia-reperfusion in mice via activation of the Nrf2 signaling pathway
por: Wang, Wen-Xi, et al.
Publicado: (2022)

Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway
por: Lv, Hongming, et al.
Publicado: (2019)

Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway
por: Liao, Hai-han, et al.
Publicado: (2019)

Pharmacological Effects of Polyphenol Phytochemicals on the JAK-STAT Signaling Pathway
por: Yin, Qianqian, et al.
Publicado: (2021)

Phytochemicals: Potential Therapeutic Modulators of Radiation Induced Signaling Pathways
por: Jit, Bimal Prasad, et al.
Publicado: (2021)

Lycopene attenuates chronic prostatitis/chronic pelvic pain syndrome by inhibiting oxidative stress and inflammation via the interaction of NF‐κB, MAPKs, and Nrf2 signaling pathways in rats
por: Zhao, Qinxin, et al.
Publicado: (2020)

The KEAP1/NRF2 Signaling Pathway in Keratinization
por: Ishitsuka, Yosuke, et al.
Publicado: (2020)

Therapeutic Targeting of the NRF2 Signaling Pathway in Cancer
por: Telkoparan-Akillilar, Pelin, et al.
Publicado: (2021)

Molecular Mechanism Underlying the Regulatory Effect of Vine Tea on Metabolic Syndrome by Targeting Redox Balance and Gut Microbiota
por: Zhou, Xixin, et al.
Publicado: (2022)

Polydatin promotes the neuronal differentiation of bone marrow mesenchymal stem cells in vitro and in vivo: Involvement of Nrf2 signalling pathway
por: Zhan, Jiheng, et al.
Publicado: (2020)

Effects of the Phytochemical Combination PB123 on Nrf2 Activation, Gene Expression, and the Cholesterol Pathway in HepG2 Cells
por: Hybertson, Brooks M., et al.
Publicado: (2022)

Ibrutinib facilitates the sensitivity of colorectal cancer cells to ferroptosis through BTK/NRF2 pathway
por: Zhu, Jin-Feng, et al.
Publicado: (2023)

Triptolide Induces Liver Injury by Regulating Macrophage Recruitment and Polarization via the Nrf2 Signaling Pathway
por: Liu, Li, et al.
Publicado: (2022)

Cold exposure induced oxidative stress and apoptosis in the myocardium by inhibiting the Nrf2-Keap1 signaling pathway
por: Cong, Peifang, et al.
Publicado: (2018)

Ursodeoxycholic Acid Protects Against Arsenic Induced Hepatotoxicity by the Nrf2 Signaling Pathway
por: Li, Chao, et al.
Publicado: (2020)

Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals
por: Wu, An-Guo, et al.
Publicado: (2022)

The Anti-Inflammatory and Anti-Oxidant Mechanisms of the Keap1/Nrf2/ARE Signaling Pathway in Chronic Diseases
por: Tu, Wenjun, et al.
Publicado: (2019)

Imperatorin exerts antioxidant effects in vascular dementia via the Nrf2 signaling pathway
por: Liao, Xiangping, et al.
Publicado: (2023)

The mechanism of Yinchenhao decoction in treating obstructive-jaundice-induced liver injury based on Nrf2 signaling pathway
por: Liu, Jun-Jian, et al.
Publicado: (2022)

7,8-Dihydroxyflavone activates Nrf2/HO-1 signaling pathways and protects against osteoarthritis
por: Cai, Dawei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5dvh83n12rhgjhepqgqt6gllis