Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19

RATIONALE: Coronavirus disease 2019 (COVID-19) can lead to acute respiratory distress syndrome with fatal outcomes. Evidence suggests that dysregulated immune responses, including autoimmunity, are key pathogenic factors. OBJECTIVES: To assess whether IgA autoantibodies target lung-specific proteins...

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Detalles Bibliográficos
Autores principales: Sinnberg, Tobias, Lichtensteiger, Christa, Ali, Omar Hasan, Pop, Oltin T., Jochum, Ann-Kristin, Risch, Lorenz, Brugger, Silvio D., Velic, Ana, Bomze, David, Kohler, Philipp, Vernazza, Pietro, Albrich, Werner C., Kahlert, Christian R., Abdou, Marie-Therese, Wyss, Nina, Hofmeister, Kathrin, Niessner, Heike, Zinner, Carl, Gilardi, Mara, Tzankov, Alexandar, Röcken, Martin, Dulovic, Alex, Shambat, Srikanth Mairpady, Ruetalo, Natalia, Buehler, Philipp K., Scheier, Thomas C., Jochum, Wolfram, Kern, Lukas, Henz, Samuel, Schneider, Tino, Kuster, Gabriela M., Lampart, Maurin, Siegemund, Martin, Bingisser, Roland, Schindler, Michael, Schneiderhan-Marra, Nicole, Kalbacher, Hubert, McCoy, Kathy D., Spengler, Werner, Brutsche, Martin H., Maček, Boris, Twerenbold, Raphael, Penninger, Josef M., Matter, Matthias S., Flatz, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952873/
https://www.ncbi.nlm.nih.gov/pubmed/35926164
http://dx.doi.org/10.1164/rccm.202201-0011OC

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