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Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune disease caused by antibodies targeting the neuromuscular junction (NJ) of skeletal muscles. The major MG autoantigen is nicotinic acetylcholine receptor. Other autoantigens at the NJ include MuSK, LRP4 and agrin. Autoantibodies to the intra-sarcomeric striated...

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Detalles Bibliográficos
Autores principales:	Stergiou, Christos, Williams, Rhys, Fleming, Jennifer R., Zouvelou, Vasiliki, Ninou, Elpinickie, Andreetta, Francesca, Rinaldi, Elena, Simoncini, Ornella, Mantegazza, Renato, Bogomolovas, Julius, Tzartos, John, Labeit, Siegfried, Mayans, Olga, Tzartos, Socrates
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952892/ https://www.ncbi.nlm.nih.gov/pubmed/36830985 http://dx.doi.org/10.3390/biomedicines11020449

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