P2X7 Receptor Modulation of the Gut Microbiota and the Inflammasome Determines the Severity of Toxoplasma gondii-Induced Ileitis

In mice, oral Toxoplasma gondii infection induces severe ileitis. The aim of the present study was to investigate the impact of the P2X7 receptor (P2X7) on the inflammatory response to T. gondii-induced ileitis. Cysts of the ME49 strain of T. gondii were used to induce ileitis. The infected mice wer...

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Detalles Bibliográficos
Autores principales: Moreira-Souza, Aline Cristina Abreu, Nanini, Hayandra Ferreira, Rangel, Thuany Prado, da Silva, Sthefani Rodrigues Batista, Damasceno, Beatriz Pêgo, Ribeiro, Beatriz Elias, Cascabulho, Cynthia M., Thompson, Fabiano, Leal, Camille, Santana, Patrícia Teixeira, Rosas, Siane Lopes Bittencourt, de Andrade, Kívia Queiroz, Silva, Claudia L. Martins, Vommaro, Rossiane Claudia, de Souza, Heitor Siffert Pereira, Coutinho-Silva, Robson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952899/
https://www.ncbi.nlm.nih.gov/pubmed/36831091
http://dx.doi.org/10.3390/biomedicines11020555

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