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Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications

Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by ch...

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Detalles Bibliográficos
Autores principales: Hama, Rikako, Ulziibayar, Anudari, Reinhardt, James W., Watanabe, Tatsuya, Kelly, John, Shinoka, Toshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953003/
https://www.ncbi.nlm.nih.gov/pubmed/36830649
http://dx.doi.org/10.3390/biom13020280
Descripción
Sumario:Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by changing the molecular structure, especially in the case of polymers. Furthermore, many high-functional hydrogels with drug delivery systems (DDSs), in which drugs or bioactive substances are contained in controlled hydrogels, have been reported. This review focuses on the molecular design and function of biopolymer-based hydrogels and introduces recent developments in functional hydrogels for clinical applications.