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Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by ch...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953003/ https://www.ncbi.nlm.nih.gov/pubmed/36830649 http://dx.doi.org/10.3390/biom13020280 |
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author | Hama, Rikako Ulziibayar, Anudari Reinhardt, James W. Watanabe, Tatsuya Kelly, John Shinoka, Toshiharu |
author_facet | Hama, Rikako Ulziibayar, Anudari Reinhardt, James W. Watanabe, Tatsuya Kelly, John Shinoka, Toshiharu |
author_sort | Hama, Rikako |
collection | PubMed |
description | Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by changing the molecular structure, especially in the case of polymers. Furthermore, many high-functional hydrogels with drug delivery systems (DDSs), in which drugs or bioactive substances are contained in controlled hydrogels, have been reported. This review focuses on the molecular design and function of biopolymer-based hydrogels and introduces recent developments in functional hydrogels for clinical applications. |
format | Online Article Text |
id | pubmed-9953003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99530032023-02-25 Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications Hama, Rikako Ulziibayar, Anudari Reinhardt, James W. Watanabe, Tatsuya Kelly, John Shinoka, Toshiharu Biomolecules Review Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by changing the molecular structure, especially in the case of polymers. Furthermore, many high-functional hydrogels with drug delivery systems (DDSs), in which drugs or bioactive substances are contained in controlled hydrogels, have been reported. This review focuses on the molecular design and function of biopolymer-based hydrogels and introduces recent developments in functional hydrogels for clinical applications. MDPI 2023-02-02 /pmc/articles/PMC9953003/ /pubmed/36830649 http://dx.doi.org/10.3390/biom13020280 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Hama, Rikako Ulziibayar, Anudari Reinhardt, James W. Watanabe, Tatsuya Kelly, John Shinoka, Toshiharu Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications |
title | Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications |
title_full | Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications |
title_fullStr | Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications |
title_full_unstemmed | Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications |
title_short | Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications |
title_sort | recent developments in biopolymer-based hydrogels for tissue engineering applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953003/ https://www.ncbi.nlm.nih.gov/pubmed/36830649 http://dx.doi.org/10.3390/biom13020280 |
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