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Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications

Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by ch...

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Detalles Bibliográficos
Autores principales: Hama, Rikako, Ulziibayar, Anudari, Reinhardt, James W., Watanabe, Tatsuya, Kelly, John, Shinoka, Toshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953003/
https://www.ncbi.nlm.nih.gov/pubmed/36830649
http://dx.doi.org/10.3390/biom13020280
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author Hama, Rikako
Ulziibayar, Anudari
Reinhardt, James W.
Watanabe, Tatsuya
Kelly, John
Shinoka, Toshiharu
author_facet Hama, Rikako
Ulziibayar, Anudari
Reinhardt, James W.
Watanabe, Tatsuya
Kelly, John
Shinoka, Toshiharu
author_sort Hama, Rikako
collection PubMed
description Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by changing the molecular structure, especially in the case of polymers. Furthermore, many high-functional hydrogels with drug delivery systems (DDSs), in which drugs or bioactive substances are contained in controlled hydrogels, have been reported. This review focuses on the molecular design and function of biopolymer-based hydrogels and introduces recent developments in functional hydrogels for clinical applications.
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spelling pubmed-99530032023-02-25 Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications Hama, Rikako Ulziibayar, Anudari Reinhardt, James W. Watanabe, Tatsuya Kelly, John Shinoka, Toshiharu Biomolecules Review Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by changing the molecular structure, especially in the case of polymers. Furthermore, many high-functional hydrogels with drug delivery systems (DDSs), in which drugs or bioactive substances are contained in controlled hydrogels, have been reported. This review focuses on the molecular design and function of biopolymer-based hydrogels and introduces recent developments in functional hydrogels for clinical applications. MDPI 2023-02-02 /pmc/articles/PMC9953003/ /pubmed/36830649 http://dx.doi.org/10.3390/biom13020280 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hama, Rikako
Ulziibayar, Anudari
Reinhardt, James W.
Watanabe, Tatsuya
Kelly, John
Shinoka, Toshiharu
Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
title Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
title_full Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
title_fullStr Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
title_full_unstemmed Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
title_short Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
title_sort recent developments in biopolymer-based hydrogels for tissue engineering applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953003/
https://www.ncbi.nlm.nih.gov/pubmed/36830649
http://dx.doi.org/10.3390/biom13020280
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