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Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification

Dementia is a cognitive disorder that mainly targets older adults. At present, dementia has no cure or prevention available. Scientists found that dementia symptoms might emerge as early as ten years before the onset of real disease. As a result, machine learning (ML) scientists developed various te...

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Autores principales: Javeed, Ashir, Dallora, Ana Luiza, Berglund, Johan Sanmartin, Idrisoglu, Alper, Ali, Liaqat, Rauf, Hafiz Tayyab, Anderberg, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953011/
https://www.ncbi.nlm.nih.gov/pubmed/36830975
http://dx.doi.org/10.3390/biomedicines11020439
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author Javeed, Ashir
Dallora, Ana Luiza
Berglund, Johan Sanmartin
Idrisoglu, Alper
Ali, Liaqat
Rauf, Hafiz Tayyab
Anderberg, Peter
author_facet Javeed, Ashir
Dallora, Ana Luiza
Berglund, Johan Sanmartin
Idrisoglu, Alper
Ali, Liaqat
Rauf, Hafiz Tayyab
Anderberg, Peter
author_sort Javeed, Ashir
collection PubMed
description Dementia is a cognitive disorder that mainly targets older adults. At present, dementia has no cure or prevention available. Scientists found that dementia symptoms might emerge as early as ten years before the onset of real disease. As a result, machine learning (ML) scientists developed various techniques for the early prediction of dementia using dementia symptoms. However, these methods have fundamental limitations, such as low accuracy and bias in machine learning (ML) models. To resolve the issue of bias in the proposed ML model, we deployed the adaptive synthetic sampling (ADASYN) technique, and to improve accuracy, we have proposed novel feature extraction techniques, namely, feature extraction battery (FEB) and optimized support vector machine (SVM) using radical basis function (rbf) for the classification of the disease. The hyperparameters of SVM are calibrated by employing the grid search approach. It is evident from the experimental results that the newly pr oposed model (FEB-SVM) improves the dementia prediction accuracy of the conventional SVM by 6%. The proposed model (FEB-SVM) obtained 98.28% accuracy on training data and a testing accuracy of 93.92%. Along with accuracy, the proposed model obtained a precision of 91.80%, recall of 86.59, F1-score of 89.12%, and Matthew’s correlation coefficient (MCC) of 0.4987. Moreover, the newly proposed model (FEB-SVM) outperforms the 12 state-of-the-art ML models that the researchers have recently presented for dementia prediction.
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spelling pubmed-99530112023-02-25 Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification Javeed, Ashir Dallora, Ana Luiza Berglund, Johan Sanmartin Idrisoglu, Alper Ali, Liaqat Rauf, Hafiz Tayyab Anderberg, Peter Biomedicines Article Dementia is a cognitive disorder that mainly targets older adults. At present, dementia has no cure or prevention available. Scientists found that dementia symptoms might emerge as early as ten years before the onset of real disease. As a result, machine learning (ML) scientists developed various techniques for the early prediction of dementia using dementia symptoms. However, these methods have fundamental limitations, such as low accuracy and bias in machine learning (ML) models. To resolve the issue of bias in the proposed ML model, we deployed the adaptive synthetic sampling (ADASYN) technique, and to improve accuracy, we have proposed novel feature extraction techniques, namely, feature extraction battery (FEB) and optimized support vector machine (SVM) using radical basis function (rbf) for the classification of the disease. The hyperparameters of SVM are calibrated by employing the grid search approach. It is evident from the experimental results that the newly pr oposed model (FEB-SVM) improves the dementia prediction accuracy of the conventional SVM by 6%. The proposed model (FEB-SVM) obtained 98.28% accuracy on training data and a testing accuracy of 93.92%. Along with accuracy, the proposed model obtained a precision of 91.80%, recall of 86.59, F1-score of 89.12%, and Matthew’s correlation coefficient (MCC) of 0.4987. Moreover, the newly proposed model (FEB-SVM) outperforms the 12 state-of-the-art ML models that the researchers have recently presented for dementia prediction. MDPI 2023-02-02 /pmc/articles/PMC9953011/ /pubmed/36830975 http://dx.doi.org/10.3390/biomedicines11020439 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Javeed, Ashir
Dallora, Ana Luiza
Berglund, Johan Sanmartin
Idrisoglu, Alper
Ali, Liaqat
Rauf, Hafiz Tayyab
Anderberg, Peter
Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification
title Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification
title_full Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification
title_fullStr Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification
title_full_unstemmed Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification
title_short Early Prediction of Dementia Using Feature Extraction Battery (FEB) and Optimized Support Vector Machine (SVM) for Classification
title_sort early prediction of dementia using feature extraction battery (feb) and optimized support vector machine (svm) for classification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953011/
https://www.ncbi.nlm.nih.gov/pubmed/36830975
http://dx.doi.org/10.3390/biomedicines11020439
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