Licochalcone E, a β-Amyloid Aggregation Inhibitor, Regulates Microglial M1/M2 Polarization via Inhibition of CTL1-Mediated Choline Uptake

Alzheimer’s disease (AD) is thought to be a series of neuroinflammatory diseases caused by abnormal deposits of amyloid-β (Aβ) and tau protein in the brain as part of its etiology. We focused on Aβ aggregation and M1 and M2 microglial polarity in microglia to search for novel therapeutic agents. It...

Descripción completa

Detalles Bibliográficos
Autores principales: Muto, Eisuke, Okada, Toshio, Yamanaka, Tsuyoshi, Uchino, Hiroyuki, Inazu, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953043/
https://www.ncbi.nlm.nih.gov/pubmed/36830561
http://dx.doi.org/10.3390/biom13020191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953043/
https://www.ncbi.nlm.nih.gov/pubmed/36830561
http://dx.doi.org/10.3390/biom13020191

Ejemplares similares