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Licochalcone E, a β-Amyloid Aggregation Inhibitor, Regulates Microglial M1/M2 Polarization via Inhibition of CTL1-Mediated Choline Uptake
Alzheimer’s disease (AD) is thought to be a series of neuroinflammatory diseases caused by abnormal deposits of amyloid-β (Aβ) and tau protein in the brain as part of its etiology. We focused on Aβ aggregation and M1 and M2 microglial polarity in microglia to search for novel therapeutic agents. It...
Autores principales: | Muto, Eisuke, Okada, Toshio, Yamanaka, Tsuyoshi, Uchino, Hiroyuki, Inazu, Masato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953043/ https://www.ncbi.nlm.nih.gov/pubmed/36830561 http://dx.doi.org/10.3390/biom13020191 |
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