Cargando…

Network Analysis for the Discovery of Common Oncogenic Biomarkers in Liver Cancer Experimental Models

Hepatocellular carcinoma (HCC) is a malignancy marked by heterogeneity. This study aimed to discover target molecules for potential therapeutic efficacy that may encompass HCC heterogeneity. In silico analysis using published datasets identified 16 proto-oncogenes as potential pharmacological target...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cabral, Loraine Kay D., Giraudi, Pablo J., Giannelli, Gianluigi, Dituri, Francesco, Negro, Roberto, Tiribelli, Claudio, Sukowati, Caecilia H. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953082/ https://www.ncbi.nlm.nih.gov/pubmed/36830879 http://dx.doi.org/10.3390/biomedicines11020342

Ejemplares similares

PD-L1 Downregulation and DNA Methylation Inhibition for Molecular Therapy against Cancer Stem Cells in Hepatocellular Carcinoma
por: Sukowati, Caecilia, et al.
Publicado: (2023)

Sorafenib Resistance in Hepatocellular Carcinoma: The Relevance of Genetic Heterogeneity
por: Cabral, Loraine Kay D., et al.
Publicado: (2020)

Circulating Long and Circular Noncoding RNA as Non-Invasive Diagnostic Tools of Hepatocellular Carcinoma
por: Sukowati, Caecilia H. C., et al.
Publicado: (2021)

The Relevance of SOCS1 Methylation and Epigenetic Therapy in Diverse Cell Populations of Hepatocellular Carcinoma
por: Cabral, Loraine Kay D., et al.
Publicado: (2021)

Immunotherapy against programmed death-1/programmed death ligand 1 in hepatocellular carcinoma: Importance of molecular variations, cellular heterogeneity, and cancer stem cells
por: Sukowati, Caecilia H C, et al.
Publicado: (2021)

The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis
por: Sukowati, Caecilia Hapsari Ceriapuri, et al.
Publicado: (2015)

Biomarkers for the Detection and Management of Hepatocellular Carcinoma in Patients Treated with Direct-Acting Antivirals
por: Cabral, Loraine Kay D., et al.
Publicado: (2022)

The mRNA Distribution of Cancer Stem Cell Marker CD90/Thy-1 Is Comparable in Hepatocellular Carcinoma of Eastern and Western Populations
por: Luong, An B., et al.
Publicado: (2020)

Correction: Aptamer: A potential oligonucleotide nanomedicine in the diagnosis and treatment of hepatocellular carcinoma
por: Ladju, Rusdina Bte, et al.
Publicado: (2018)

Aptamer: A potential oligonucleotide nanomedicine in the diagnosis and treatment of hepatocellular carcinoma
por: Ladju, Rusdina Bte, et al.
Publicado: (2017)

The Expression Level of ABCC6 Transporter in Colon Cancer Cells Correlates with the Activation of Different Intracellular Signaling Pathways
por: Abruzzese, Vittorio, et al.
Publicado: (2022)

Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA
por: Bianca, Claryssa, et al.
Publicado: (2022)

The Expression of CD90/Thy-1 in Hepatocellular Carcinoma: An In Vivo and In Vitro Study
por: Sukowati, Caecilia Hapsari Ceriapuri, et al.
Publicado: (2013)

MutL homolog 1 methylation and microsatellite instability in sporadic colorectal tumors among Filipinos
por: Cabral, Loraine Kay D, et al.
Publicado: (2021)

Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma
por: Sukowati, Caecilia HC, et al.
Publicado: (2012)

Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma
por: Pascut, Devis, et al.
Publicado: (2019)

Silybin Modulates Collagen Turnover in an In Vitro Model of NASH
por: Anfuso, Beatrice, et al.
Publicado: (2019)

Natural Compounds for Counteracting Nonalcoholic Fatty Liver Disease (NAFLD): Advantages and Limitations of the Suggested Candidates
por: Salvoza, Noel, et al.
Publicado: (2022)

Validation of Hepatocellular Carcinoma Experimental Models for TGF-β Promoting Tumor Progression
por: Mancarella, Serena, et al.
Publicado: (2019)

Diagnostic management of nonalcoholic fatty liver disease: a transformational period in the development of diagnostic and predictive tools—a narrative review
por: Rosso, Natalia, et al.
Publicado: (2021)

Activation of hepatic stem cells compartment during hepatocarcinogenesis in a HBsAg HBV-transgenic mouse model
por: Anfuso, Beatrice, et al.
Publicado: (2018)

Hyaluronic acid inhibition by 4-methylumbelliferone reduces the expression of cancer stem cells markers during hepatocarcinogenesis
por: Sukowati, Caecilia H. C., et al.
Publicado: (2019)

PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors
por: Dituri, Francesco, et al.
Publicado: (2011)

Transforming Growth Factor-β Promotes Morphomechanical Effects Involved in Epithelial to Mesenchymal Transition in Living Hepatocellular Carcinoma
por: Cascione, Mariafrancesca, et al.
Publicado: (2018)

The Interactivity between TGFβ and BMP Signaling in Organogenesis, Fibrosis, and Cancer
por: Dituri, Francesco, et al.
Publicado: (2019)

Laminin-332 γ2 Monomeric Chain Promotes Adhesion and Migration of Hepatocellular Carcinoma Cells
por: Scialpi, Rosanna, et al.
Publicado: (2023)

Serum Stem Cell Growth Factor Beta for the Prediction of Therapy Response in Hepatocellular Carcinoma
por: Sukowati, Caecilia H. C., et al.
Publicado: (2018)

Updating the Clinical Application of Blood Biomarkers and Their Algorithms in the Diagnosis and Surveillance of Hepatocellular Carcinoma: A Critical Review
por: Shahini, Endrit, et al.
Publicado: (2023)

NGS-based transcriptome profiling reveals biomarkers for companion diagnostics of the TGF-β receptor blocker galunisertib in HCC
por: Cao, Yuan, et al.
Publicado: (2017)

Proteoglycans in Cancer: Friends or Enemies? A Special Focus on Hepatocellular Carcinoma
por: Dituri, Francesco, et al.
Publicado: (2022)

Calcium Regulates HCC Proliferation as well as EGFR Recycling/Degradation and Could Be a New Therapeutic Target in HCC
por: Modica, Teresa Maria Elisa, et al.
Publicado: (2019)

Impaired Anti-Tumor T cell Response in Hepatocellular Carcinoma
por: Chaoul, Nada, et al.
Publicado: (2020)

Functional Induction of the Cystine-Glutamate Exchanger System X(c) (-) Activity in SH-SY5Y Cells by Unconjugated Bilirubin
por: Giraudi, Pablo J., et al.
Publicado: (2011)

Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome
por: Pascut, Devis, et al.
Publicado: (2023)

Ethnogeographical structure of hepatitis B virus genotype distribution in Indonesia and discovery of a new subgenotype, B9
por: Thedja, Meta Dewi, et al.
Publicado: (2011)

Artificial Intelligence and Complex Network Approaches Reveal Potential Gene Biomarkers for Hepatocellular Carcinoma
por: Lacalamita, Antonio, et al.
Publicado: (2023)

Updates on Organoid Model for the Study of Liver Cancer
por: El-Khobar, Korri E., et al.
Publicado: (2023)

Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models
por: Centonze, Matteo, et al.
Publicado: (2023)

Correction: Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models
por: Centonze, Matteo, et al.
Publicado: (2023)

A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells
por: Calligaris, Raffaella, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_6a1fse62en69mtss65khe2o2bd