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The Fuzzy Border between the Functional and Dysfunctional Effects of Beta-Amyloid: A Synaptocentric View of Neuron–Glia Entanglement

Recent observations from clinical trials using monoclonal antibodies against Aβ seem to suggest that Aβ-targeting is modestly effective and not sufficiently based on an effective challenge of the role of Aβ from physiological to pathological. After an accelerated approval procedure for aducanumab, a...

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Detalles Bibliográficos
Autores principales: Fagiani, Francesca, Fulop, Tamas, Govoni, Stefano, Lanni, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953143/
https://www.ncbi.nlm.nih.gov/pubmed/36831020
http://dx.doi.org/10.3390/biomedicines11020484