Pharmacokinetic Evaluation of New Drugs Using a Multi-Labelling Approach and PET Imaging: Application to a Drug Candidate with Potential Application in Neuromuscular Disorders

Background and objective: The determination of pharmacokinetic properties of new chemical entities is a key step in the process of drug development. Positron emission tomography (PET) is an ideal technique to obtain both biodistribution and pharmacokinetic parameters of new compounds over a wide ran...

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Detalles Bibliográficos
Autores principales: Passannante, Rossana, Gómez-Vallejo, Vanessa, Sagartzazu-Aizpurua, Maialen, Vignau Arsuaga, Laura, Marco-Moreno, Pablo, Aldanondo, Garazi, Vallejo-Illarramendi, Ainara, Aguiar, Pablo, Cossío, Unai, Martín, Abraham, Bergare, Jonas, Kingston, Lee, Elmore, Charles S., Morcillo, Miguel Angel, Ferrón, Pablo, Aizpurua, Jesus M., Llop, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953224/
https://www.ncbi.nlm.nih.gov/pubmed/36830793
http://dx.doi.org/10.3390/biomedicines11020253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953224/
https://www.ncbi.nlm.nih.gov/pubmed/36830793
http://dx.doi.org/10.3390/biomedicines11020253

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