Structural Characterization of Nanobodies during Germline Maturation

Camelid heavy-chain antibody variable domains (V(H)H), nanobodies, are the smallest-known functional antibody fragments with high therapeutic potential. In this study, we investigate a V(H)H binding to hen egg-white lysozyme (HEL). We structurally and dynamically characterized the conformational div...

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Detalles Bibliográficos
Autores principales: Seidler, Clarissa A., Kokot, Janik, Fernández-Quintero, Monica L., Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953242/
https://www.ncbi.nlm.nih.gov/pubmed/36830754
http://dx.doi.org/10.3390/biom13020380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953242/
https://www.ncbi.nlm.nih.gov/pubmed/36830754
http://dx.doi.org/10.3390/biom13020380

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