Impaired Function of Solute Carrier Family 19 Leads to Low Folate Levels and Lipid Droplet Accumulation in Hepatocytes

Low serum folate levels are inversely related to metabolic associated fatty liver disease (MAFLD). The role of the folate transporter gene (SLC19A1) was assessed to clarify its involvement in lipid accumulation during the onset of MAFLD in humans and in liver cells by genomic, transcriptomic, and me...

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Detalles Bibliográficos
Autores principales: Cano, Ainara, Vazquez-Chantada, Mercedes, Conde-Vancells, Javier, Gonzalez-Lahera, Aintzane, Mosen-Ansorena, David, Blanco, Francisco J., Clément, Karine, Aron-Wisnewsky, Judith, Tran, Albert, Gual, Philippe, García-Monzón, Carmelo, Caballería, Joan, Castro, Azucena, Martínez-Chantar, María Luz, Mato, José M., Zhu, Huiping, Finnell, Richard H., Aransay, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953281/
https://www.ncbi.nlm.nih.gov/pubmed/36830876
http://dx.doi.org/10.3390/biomedicines11020337

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