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Progression of Thoracic Aortic Dissection Is Aggravated by the hsa_circ_0007386/miR-1271-5P/IGF1R/AKT Axis via Induction of Arterial Smooth Muscle Cell Apoptosis

Background: The molecular mechanisms associated with thoracic aortic dissection (TAD) remain poorly understood. A comprehensive high-throughput sequencing-based analysis of the circRNA–miRNA–mRNA competitive endogenous RNA (ceRNA) regulatory network in TAD has not been conducted. The purpose of this...

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Detalles Bibliográficos
Autores principales: Xie, Xinsheng, Hong, Xiang, Hong, Shichai, Huang, Yulong, Chen, Gang, Chen, Yihui, Lin, Yue, Lu, Weifeng, Fu, Weiguo, Wang, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953311/
https://www.ncbi.nlm.nih.gov/pubmed/36831107
http://dx.doi.org/10.3390/biomedicines11020571