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Copper Binding and Redox Activity of α-Synuclein in Membrane-Like Environment
α-Synuclein (αSyn) constitutes the main protein component of Lewy bodies, which are the pathologic hallmark in Parkinson’s disease. αSyn is unstructured in solution but the interaction of αSyn with lipid membrane modulates its conformation by inducing an α-helical structure of the N-terminal region....
Autores principales: | Bacchella, Chiara, Camponeschi, Francesca, Kolkowska, Paulina, Kola, Arian, Tessari, Isabella, Baratto, Maria Camilla, Bisaglia, Marco, Monzani, Enrico, Bubacco, Luigi, Mangani, Stefano, Casella, Luigi, Dell’Acqua, Simone, Valensin, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953312/ https://www.ncbi.nlm.nih.gov/pubmed/36830656 http://dx.doi.org/10.3390/biom13020287 |
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