Augmented Ouabain-Induced Vascular Response Reduces Cardiac Efficiency in Mice with Migraine-Associated Mutation in the Na(+), K(+)-ATPase α(2)-Isoform

Heterozygous mice (α(2)(+/G301R) mice) for the migraine-associated mutation (G301R) in the Na(+),K(+)-ATPase α(2)-isoform have decreased expression of cardiovascular α(2)-isoform. The α(2)(+/G301R) mice exhibit a pro-contractile vascular phenotype associated with decreased left ventricular ejection...

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Detalles Bibliográficos
Autores principales: Rajanathan, Rajkumar, Pedersen, Tina Myhre, Guldbrandsen, Halvor Osterby, Olesen, Lenette Foldager, Thomsen, Morten B., Bøtker, Hans Erik, Matchkov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953359/
https://www.ncbi.nlm.nih.gov/pubmed/36830881
http://dx.doi.org/10.3390/biomedicines11020344

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