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Pimozide Increases a Delayed Rectifier K(+) Conductance in Chicken Embryo Vestibular Hair Cells

Pimozide is a conventional antipsychotic drug largely used in the therapy for schizophrenia and Tourette’s syndrome. Pimozide is assumed to inhibit synaptic transmission at the CNS by acting as a dopaminergic D(2) receptor antagonist. Moreover, pimozide has been shown to block voltage-gated Ca(2+) a...

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Detalles Bibliográficos
Autores principales: Giunta, Roberta, Cheli, Giulia, Spaiardi, Paolo, Russo, Giancarlo, Masetto, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953418/
https://www.ncbi.nlm.nih.gov/pubmed/36831024
http://dx.doi.org/10.3390/biomedicines11020488