Cargando…
Pimozide Increases a Delayed Rectifier K(+) Conductance in Chicken Embryo Vestibular Hair Cells
Pimozide is a conventional antipsychotic drug largely used in the therapy for schizophrenia and Tourette’s syndrome. Pimozide is assumed to inhibit synaptic transmission at the CNS by acting as a dopaminergic D(2) receptor antagonist. Moreover, pimozide has been shown to block voltage-gated Ca(2+) a...
Autores principales: | Giunta, Roberta, Cheli, Giulia, Spaiardi, Paolo, Russo, Giancarlo, Masetto, Sergio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953418/ https://www.ncbi.nlm.nih.gov/pubmed/36831024 http://dx.doi.org/10.3390/biomedicines11020488 |
Ejemplares similares
-
Current Response in Ca(V)1.3(–/–) Mouse Vestibular and Cochlear Hair Cells
por: Manca, Marco, et al.
Publicado: (2021) -
Signal transmission in mature mammalian vestibular hair cells
por: Spaiardi, Paolo, et al.
Publicado: (2022) -
K(+) Accumulation and Clearance in the Calyx Synaptic Cleft of Type I Mouse Vestibular Hair Cells
por: Spaiardi, P., et al.
Publicado: (2020) -
An allosteric gating model recapitulates the biophysical properties of I
(K,L) expressed in mouse vestibular type I hair cells
por: Spaiardi, Paolo, et al.
Publicado: (2017) -
Exocytosis in mouse vestibular Type II hair cells shows a high‐order Ca(2+) dependence that is independent of synaptotagmin‐4
por: Spaiardi, Paolo, et al.
Publicado: (2020)