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Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs

Background: Kivach Clinic has developed a special medical spa program to prevent aging-related conditions in metabolic, cardio-vascular, and neurological states. Spa programs modify diet, physical activity, and lymphatic drainage, as it deteriorates with aging. We investigated its influence on the b...

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Autores principales: Isaev, Fedor I., Sadykov, Arsenii R., Moskalev, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953453/
https://www.ncbi.nlm.nih.gov/pubmed/36831161
http://dx.doi.org/10.3390/biomedicines11020625
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author Isaev, Fedor I.
Sadykov, Arsenii R.
Moskalev, Alexey
author_facet Isaev, Fedor I.
Sadykov, Arsenii R.
Moskalev, Alexey
author_sort Isaev, Fedor I.
collection PubMed
description Background: Kivach Clinic has developed a special medical spa program to prevent aging-related conditions in metabolic, cardio-vascular, and neurological states. Spa programs modify diet, physical activity, and lymphatic drainage, as it deteriorates with aging. We investigated its influence on the blood markers of biological age of patients during their stay to objectify the potential of spa treatment for influencing the risk of age-related events. Methods: The artificial deep learning model Aging.ai 3.0 was based on blood parameters. The change in the biological age of 43 patients was assessed after their 14-day spa treatment at Kivach Clinic. Results: Biological age decreased in 29 patients (median decrease: 8 years, mean: 8.83 years), increased in 10 patients (median increase: 3 years, mean: 5.33 years) and remained unchanged in 4 patients. Overall mean values for the entire patient group were as follows: median value was −3 years, and mean was −4.79 ± 1.2 years (p-value = 0.00025, t-test). Conclusions: The capability of specially selected medical spa treatment to reduce human biological age (assessed by Aging.AI 3.0) has been established.
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spelling pubmed-99534532023-02-25 Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs Isaev, Fedor I. Sadykov, Arsenii R. Moskalev, Alexey Biomedicines Brief Report Background: Kivach Clinic has developed a special medical spa program to prevent aging-related conditions in metabolic, cardio-vascular, and neurological states. Spa programs modify diet, physical activity, and lymphatic drainage, as it deteriorates with aging. We investigated its influence on the blood markers of biological age of patients during their stay to objectify the potential of spa treatment for influencing the risk of age-related events. Methods: The artificial deep learning model Aging.ai 3.0 was based on blood parameters. The change in the biological age of 43 patients was assessed after their 14-day spa treatment at Kivach Clinic. Results: Biological age decreased in 29 patients (median decrease: 8 years, mean: 8.83 years), increased in 10 patients (median increase: 3 years, mean: 5.33 years) and remained unchanged in 4 patients. Overall mean values for the entire patient group were as follows: median value was −3 years, and mean was −4.79 ± 1.2 years (p-value = 0.00025, t-test). Conclusions: The capability of specially selected medical spa treatment to reduce human biological age (assessed by Aging.AI 3.0) has been established. MDPI 2023-02-19 /pmc/articles/PMC9953453/ /pubmed/36831161 http://dx.doi.org/10.3390/biomedicines11020625 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Isaev, Fedor I.
Sadykov, Arsenii R.
Moskalev, Alexey
Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs
title Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs
title_full Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs
title_fullStr Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs
title_full_unstemmed Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs
title_short Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs
title_sort blood markers of biological age evaluates clinic complex medical spa programs
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953453/
https://www.ncbi.nlm.nih.gov/pubmed/36831161
http://dx.doi.org/10.3390/biomedicines11020625
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