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Development of a Sensitive Digital Droplet PCR Screening Assay for the Detection of GPR126 Non-Coding Mutations in Bladder Cancer Urine Liquid Biopsies
Recent whole-genome sequencing studies identified two novel recurrent mutations in the enhancer region of GPR126 in urothelial bladder cancer (UBC) tumor samples. This mutational hotspot is the second most common after the TERT promoter in UBC. The aim of the study was to develop a digital droplet P...
Autores principales: | Jain, Mark, Tivtikyan, Alexander, Kamalov, David, Avdonin, Savva, Rakhmatullin, Tagir, Pisarev, Eduard, Zvereva, Maria, Samokhodskaya, Larisa, Kamalov, Armais |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953558/ https://www.ncbi.nlm.nih.gov/pubmed/36831030 http://dx.doi.org/10.3390/biomedicines11020495 |
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