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Development of a Sensitive Digital Droplet PCR Screening Assay for the Detection of GPR126 Non-Coding Mutations in Bladder Cancer Urine Liquid Biopsies

Recent whole-genome sequencing studies identified two novel recurrent mutations in the enhancer region of GPR126 in urothelial bladder cancer (UBC) tumor samples. This mutational hotspot is the second most common after the TERT promoter in UBC. The aim of the study was to develop a digital droplet P...

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Detalles Bibliográficos
Autores principales: Jain, Mark, Tivtikyan, Alexander, Kamalov, David, Avdonin, Savva, Rakhmatullin, Tagir, Pisarev, Eduard, Zvereva, Maria, Samokhodskaya, Larisa, Kamalov, Armais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953558/
https://www.ncbi.nlm.nih.gov/pubmed/36831030
http://dx.doi.org/10.3390/biomedicines11020495

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