Gene–Environment Interactions in Repeat Expansion Diseases: Mechanisms of Environmentally Induced Repeat Instability

Short tandem repeats (STRs) are units of 1–6 base pairs that occur in tandem repetition to form a repeat tract. STRs exhibit repeat instability, which generates expansions or contractions of the repeat tract. Over 50 diseases, primarily affecting the central nervous system and muscles, are character...

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Detalles Bibliográficos
Autores principales: Calluori, Stephanie, Stark, Rebecca, Pearson, Brandon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953593/
https://www.ncbi.nlm.nih.gov/pubmed/36831049
http://dx.doi.org/10.3390/biomedicines11020515

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