Cargando…
Role of Astrocytes in Parkinson’s Disease Associated with Genetic Mutations and Neurotoxicants
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons and the aggregation of Lewy bodies in the basal ganglia, resulting in movement impairment referred to as parkinsonism. However, the etiology of PD is not well known, with genetic factors accoun...
Autores principales: | Kim, Sanghoon, Pajarillo, Edward, Nyarko-Danquah, Ivan, Aschner, Michael, Lee, Eunsook |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953822/ https://www.ncbi.nlm.nih.gov/pubmed/36831289 http://dx.doi.org/10.3390/cells12040622 |
Ejemplares similares
-
Astrocytic Oxidative/Nitrosative Stress Contributes to Parkinson’s Disease Pathogenesis: The Dual Role of Reactive Astrocytes
por: Rizor, Asha, et al.
Publicado: (2019) -
Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity
por: Pajarillo, Edward, et al.
Publicado: (2021) -
Mechanisms of manganese-induced neurotoxicity and the pursuit of neurotherapeutic strategies
por: Pajarillo, Edward, et al.
Publicado: (2022) -
Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms
por: Nyarko-Danquah, Ivan, et al.
Publicado: (2020) -
The role of microglial LRRK2 kinase in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction
por: Pajarillo, Edward, et al.
Publicado: (2023)