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The Role of CREBBP/EP300 and Its Therapeutic Implications in Hematological Malignancies

SIMPLE SUMMARY: Through their regulatory effects on gene expression, histone acetyltransferases have been implicated in the normal physiological activities and genesis of cancer. Genetic aberrations of CREBBP/EP300 have been observed in various types of solid tumors and hematologic malignancies, mak...

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Detalles Bibliográficos
Autores principales: Zhu, Yu, Wang, Zi, Li, Yanan, Peng, Hongling, Liu, Jing, Zhang, Ji, Xiao, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953837/
https://www.ncbi.nlm.nih.gov/pubmed/36831561
http://dx.doi.org/10.3390/cancers15041219