Cargando…
Ranitidine Alleviates Anxiety-like Behaviors and Improves the Density of Pyramidal Neurons upon Deactivation of Microglia in the CA3 Region of the Hippocampus in a Cysteamine HCl-Induced Mouse Model of Gastrointestinal Disorder
Elevated levels of histamine cause over-secretion of gastric hydrochloric acid (HCl), leading to gastrointestinal (GI) disorders and anxiety. Ranitidine is an antihistamine drug widely used in the management of GI disorders, as it works by blocking the histamine−2 receptors in parietal cells, thereb...
Autores principales: | Selvaraj, Divya Bharathi, Vergil Andrews, Jemi Feiona, Anusuyadevi, Muthuswamy, Kandasamy, Mahesh |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953842/ https://www.ncbi.nlm.nih.gov/pubmed/36831809 http://dx.doi.org/10.3390/brainsci13020266 |
Ejemplares similares
-
A Mild Dose of Aspirin Promotes Hippocampal Neurogenesis and Working Memory in Experimental Ageing Mice
por: Vergil Andrews, Jemi Feiona, et al.
Publicado: (2023) -
Omeprazole treatment manifests anxiolytic effects in a cysteamine hydrochloride induced mouse model of gastrointestinal disorder
por: Sri Rethinavel, Harini, et al.
Publicado: (2022) -
Resveratrol Mediated Regulation of Hippocampal Neuroregenerative Plasticity via SIRT1 Pathway in Synergy with Wnt Signaling: Neurotherapeutic Implications to Mitigate Memory Loss in Alzheimer’s Disease
por: Surya, Kumar, et al.
Publicado: (2023) -
Pathogenomic Signature and Aberrant Neurogenic Events in Experimental Cerebral Ischemic Stroke: A Neurotranscriptomic-Based Implication for Dementia
por: Roshan, Syed Aasish, et al.
Publicado: (2023) -
In Vitro and In Vivo Evaluation of Composite Oral Fast Disintegrating Film: An Innovative Strategy for the Codelivery of Ranitidine HCl and Flurbiprofen
por: Rashid, Aisha, et al.
Publicado: (2023)