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Hypoxia, a Targetable Culprit to Counter Pancreatic Cancer Resistance to Therapy

SIMPLE SUMMARY: Hypoxia is a key feature of the tumor microenvironment involved in the pathogenesis of pancreatic ductal adenocarcinoma (PDAC). In this review we will highlight hypoxia’s integral role in shaping genomic instability and the tumor immune microenvironment in this disease. We will furth...

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Detalles Bibliográficos
Autores principales: Abou Khouzam, Raefa, Lehn, Jean-Marie, Mayr, Hemma, Clavien, Pierre-Alain, Wallace, Michael Bradley, Ducreux, Michel, Limani, Perparim, Chouaib, Salem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953896/
https://www.ncbi.nlm.nih.gov/pubmed/36831579
http://dx.doi.org/10.3390/cancers15041235