Cargando…
Hypoxia, a Targetable Culprit to Counter Pancreatic Cancer Resistance to Therapy
SIMPLE SUMMARY: Hypoxia is a key feature of the tumor microenvironment involved in the pathogenesis of pancreatic ductal adenocarcinoma (PDAC). In this review we will highlight hypoxia’s integral role in shaping genomic instability and the tumor immune microenvironment in this disease. We will furth...
Autores principales: | Abou Khouzam, Raefa, Lehn, Jean-Marie, Mayr, Hemma, Clavien, Pierre-Alain, Wallace, Michael Bradley, Ducreux, Michel, Limani, Perparim, Chouaib, Salem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953896/ https://www.ncbi.nlm.nih.gov/pubmed/36831579 http://dx.doi.org/10.3390/cancers15041235 |
Ejemplares similares
-
The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes?
por: Abou Khouzam, Raefa, et al.
Publicado: (2022) -
An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment
por: Abou Khouzam, Raefa, et al.
Publicado: (2021) -
Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity?
por: Hassan Venkatesh, Goutham, et al.
Publicado: (2021) -
Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies
por: Abou Khouzam, Raefa, et al.
Publicado: (2021) -
Parastomal gallbladder herniation: A case report and review of the literature
por: Moeckli, Beat, et al.
Publicado: (2020)