Decoupling of mRNA and Protein Expression in Aging Brains Reveals the Age-Dependent Adaptation of Specific Gene Subsets

During aging, changes in gene expression are associated with a decline in physical and cognitive abilities. Here, we investigate the connection between changes in mRNA and protein expression in the brain by comparing the transcriptome and proteome of the mouse cortex during aging. Our transcriptomic...

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Detalles Bibliográficos
Autores principales: Khatir, Inès, Brunet, Marie A., Meller, Anna, Amiot, Florent, Patel, Tushar, Lapointe, Xavier, Avila Lopez, Jessica, Guilloy, Noé, Castonguay, Anne, Husain, Mohammed Amir, Germain, Joannie St., Boisvert, François-Michel, Plourde, Mélanie, Roucou, Xavier, Laurent, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954025/
https://www.ncbi.nlm.nih.gov/pubmed/36831282
http://dx.doi.org/10.3390/cells12040615

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