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Uptake and Effectiveness of Risk-Reducing Surgeries in Unaffected Female BRCA1 and BRCA2 Carriers: A Single Institution Experience in the Czech Republic
SIMPLE SUMMARY: Women with BRCA 1/2 pathogenic/likely pathogenic variants (P/LPVs) have a high lifetime risk of developing breast and ovarian cancer. The aim of the retrospective study is to analyze the rate, longitudinal trends, and effectiveness of prophylactic risk-reducing mastectomy (RRM) and s...
Autores principales: | Zimovjanova, Martina, Bielcikova, Zuzana, Miskovicova, Michaela, Vocka, Michal, Zimovjanova, Anna, Rybar, Marian, Novotny, Jan, Petruzelka, Lubos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954081/ https://www.ncbi.nlm.nih.gov/pubmed/36831416 http://dx.doi.org/10.3390/cancers15041072 |
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