Pluripotent Stem Cells in Disease Modeling and Drug Discovery for Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1) is a progressive multisystemic disease caused by the expansion of a CTG repeat tract within the 3′ untranslated region (3′ UTR) of the dystrophia myotonica protein kinase gene (DMPK). Although DM1 is considered to be the most frequent myopathy of genetic origin in adu...

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Detalles Bibliográficos
Autores principales: Bérenger-Currias, Noémie, Martinat, Cécile, Baghdoyan, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954118/
https://www.ncbi.nlm.nih.gov/pubmed/36831237
http://dx.doi.org/10.3390/cells12040571

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