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Anti-Leukaemic Activity of Rilpivirine Is Mediated by Aurora A Kinase Inhibition

SIMPLE SUMMARY: Rilpivirine is an anti-viral drug used for treating human immunodeficiency virus (HIV) patients. In a recent study, we demonstrated that rilpivirine inhibited Aurora A, a protein kinase that mainly regulates the mitotic events of the cell-division cycle. Importantly, Aurora A kinase...

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Detalles Bibliográficos
Autores principales: Islam, Saiful, Rahaman, Muhammed H., Yu, Mingfeng, Noll, Benjamin, Martin, Jennifer H., Wang, Shudong, Head, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954146/
https://www.ncbi.nlm.nih.gov/pubmed/36831387
http://dx.doi.org/10.3390/cancers15041044

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