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Anti-Leukaemic Activity of Rilpivirine Is Mediated by Aurora A Kinase Inhibition
SIMPLE SUMMARY: Rilpivirine is an anti-viral drug used for treating human immunodeficiency virus (HIV) patients. In a recent study, we demonstrated that rilpivirine inhibited Aurora A, a protein kinase that mainly regulates the mitotic events of the cell-division cycle. Importantly, Aurora A kinase...
Autores principales: | Islam, Saiful, Rahaman, Muhammed H., Yu, Mingfeng, Noll, Benjamin, Martin, Jennifer H., Wang, Shudong, Head, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954146/ https://www.ncbi.nlm.nih.gov/pubmed/36831387 http://dx.doi.org/10.3390/cancers15041044 |
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