Drug Resistance in Medulloblastoma Is Driven by YB-1, ABCB1 and a Seven-Gene Drug Signature

SIMPLE SUMMARY: Medulloblastoma is the most common malignant childhood brain tumour. Under standard therapy, relapse occurs in 30% of patients and is almost universally fatal, accounting for 10% of all childhood cancer deaths. A barrier to effective medulloblastoma treatment is cellular resistance t...

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Detalles Bibliográficos
Autores principales: Taylor, Louisa, Wade, Philippa K., Johnson, James E. C., Aldighieri, Macha, Morlando, Sonia, Di Leva, Gianpiero, Kerr, Ian D., Coyle, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954169/
https://www.ncbi.nlm.nih.gov/pubmed/36831428
http://dx.doi.org/10.3390/cancers15041086

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