Cargando…

Administration of Secretome Derived from Human Mesenchymal Stem Cells Induces Hepatoprotective Effects in Models of Idiosyncratic Drug-Induced Liver Injury Caused by Amiodarone or Tamoxifen

Drug-induced liver injury (DILI) is one of the leading causes of acute liver injury. While many factors may contribute to the susceptibility to DILI, obese patients with hepatic steatosis are particularly prone to suffer DILI. The secretome derived from mesenchymal stem cell has been shown to have h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Ya-Lin, De Gregorio, Cristian, Silva, Verónica, Elorza, Álvaro A., Léniz, Patricio, Aliaga-Tobar, Víctor, Maracaja-Coutinho, Vinicius, Budini, Mauricio, Ezquer, Fernando, Ezquer, Marcelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954258/ https://www.ncbi.nlm.nih.gov/pubmed/36831304 http://dx.doi.org/10.3390/cells12040636

Ejemplares similares

Human adipose-derived mesenchymal stem cell-conditioned medium ameliorates polyneuropathy and foot ulceration in diabetic BKS db/db mice
por: De Gregorio, Cristian, et al.
Publicado: (2020)

Preconditioning of adipose tissue-derived mesenchymal stem cells with deferoxamine increases the production of pro-angiogenic, neuroprotective and anti-inflammatory factors: Potential application in the treatment of diabetic neuropathy
por: Oses, Carolina, et al.
Publicado: (2017)

Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence
por: Quintanilla, María Elena, et al.
Publicado: (2022)

Characterization of diabetic neuropathy progression in a mouse model of type 2 diabetes mellitus
por: De Gregorio, Cristian, et al.
Publicado: (2018)

Improving Cell Recovery: Freezing and Thawing Optimization of Induced Pluripotent Stem Cells
por: Uhrig, Markus, et al.
Publicado: (2022)

Sensory neuron cultures derived from adult db/db mice as a simplified model to study type-2 diabetes-associated axonal regeneration defects
por: De Gregorio, Cristian, et al.
Publicado: (2021)

New Perspectives to Improve Mesenchymal Stem Cell Therapies for Drug-Induced Liver Injury
por: Ezquer, Fernando, et al.
Publicado: (2022)

Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options
por: Quintanilla, María Elena, et al.
Publicado: (2019)

A regulatory RNA is involved in RNA duplex formation and biofilm regulation in Sulfolobus acidocaldarius
por: Orell, Alvaro, et al.
Publicado: (2018)

The Antidiabetic Effect of MSCs Is Not Impaired by Insulin Prophylaxis and Is Not Improved by a Second Dose of Cells
por: Ezquer, Fernando, et al.
Publicado: (2011)

Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3)
por: Figueroa, Vania A., et al.
Publicado: (2020)

Corrigendum: Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3)
por: Figueroa, Vania A., et al.
Publicado: (2020)

Amiodarone: Amiodarone-induced thyrotoxicosis: case report
Publicado: (2022)

Administration of multipotent mesenchymal stromal cells restores liver regeneration and improves liver function in obese mice with hepatic steatosis after partial hepatectomy
por: Ezquer, Fernando, et al.
Publicado: (2017)

A Novel Morphine Drinking Model of Opioid Dependence in Rats
por: Berríos-Cárcamo, Pablo, et al.
Publicado: (2022)

Hepatoprotection by active fractions from Desmostachya bipinnata stapf (L.) against tamoxifen-induced hepatotoxicity
por: Rahate, Kalpana Pravin, et al.
Publicado: (2015)

High Fat Diet-Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis
por: Abrigo, Johanna, et al.
Publicado: (2016)

Drug-Induced Idiosyncratic Agranulocytosis - Infrequent but Dangerous
por: Rattay, Bernd, et al.
Publicado: (2021)

Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue receptivity
por: Ezquer, Fernando E., et al.
Publicado: (2016)

Oxidative Stress and Neuroinflammation as a Pivot in Drug Abuse. A Focus on the Therapeutic Potential of Antioxidant and Anti-Inflammatory Agents and Biomolecules
por: Berríos-Cárcamo, Pablo, et al.
Publicado: (2020)

Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice
por: Ezquer, Marcelo, et al.
Publicado: (2016)

Proregenerative Microenvironment Triggered by Donor Mesenchymal Stem Cells Preserves Renal Function and Structure in Mice with Severe Diabetes Mellitus
por: Ezquer, Fernando, et al.
Publicado: (2015)

Electrocardiographic changes in patients with tramadol-induced idiosyncratic seizures
por: Hafezi Moghadam, Peyman, et al.
Publicado: (2016)

Immune mechanisms of idiosyncratic drug-induced liver injury
por: Mak, Alastair, et al.
Publicado: (2017)

Idiosyncratic Drug-Induced Neutropenia and Agranulocytosis in Elderly Patients
por: Lorenzo-Villalba, Noel, et al.
Publicado: (2020)

Isotretinoin Induced Pancreatitis: A Rare Idiosyncratic Reaction
por: Dhattarwal, Niharika, et al.
Publicado: (2022)

Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: hopes and fears
por: Ezquer, Fernando, et al.
Publicado: (2015)

Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats
por: Quintanilla, María Elena, et al.
Publicado: (2021)

Amiodarone-induced Hepatitis and Polyneuropathy
por: Kang, Hyun Mo, et al.
Publicado: (2007)

Amiodarone induced epididymo-orchitis
por: Dasu, Neethi, et al.
Publicado: (2019)

Amiodarone-Induced Myxedema Coma
por: Raeouf, Armaghan, et al.
Publicado: (2020)

Amiodarone induced lung disease
por: Mitrofan, Cristina Elena, et al.
Publicado: (2022)

Comparative Profiling of Circulating Exosomal Small RNAs Derived From Peruvian Patients With Tuberculosis and Pulmonary Adenocarcinoma
por: Guio, Heinner, et al.
Publicado: (2022)

Genome‐wide analysis of in vivo CcpA binding with and without its key co‐factor HPr in the major human pathogen group A Streptococcus
por: DebRoy, Sruti, et al.
Publicado: (2020)

Update on Advances in Research on Idiosyncratic Drug-Induced Liver Injury
por: Kim, Seung-Hyun, et al.
Publicado: (2016)

Idiosyncratic drug‐induced liver injury: A short review
por: Yamashita, Yo‐ichi, et al.
Publicado: (2017)

Treatment of Idiosyncratic Drug-Induced Liver Injury Using Steroids
por: Sundaram, Suneha, et al.
Publicado: (2020)

Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges
por: Jee, Alison, et al.
Publicado: (2021)

The idiosyncratic nature of confidence
por: Navajas, Joaquin, et al.
Publicado: (2017)

Amiodarone-Induced Liver Injury and Cirrhosis
por: Buggey, Jonathan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_smkkujt7l9kaa4h36aftc4k648