Alzheimer’s Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins

Genetic variations of CD33 have been implicated as a susceptibility factor of Alzheimer’s disease (AD). A polymorphism on exon 2 of CD33, rs12459419, affects the alternative splicing of this exon. The minor allele is associated with a reduced risk of AD and promotes the skipping of exon 2 to produce...

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Detalles Bibliográficos
Autores principales: Komuro, Riho, Honda, Yuka, Yanaizu, Motoaki, Nagahama, Masami, Kino, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954446/
https://www.ncbi.nlm.nih.gov/pubmed/36831269
http://dx.doi.org/10.3390/cells12040602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954446/
https://www.ncbi.nlm.nih.gov/pubmed/36831269
http://dx.doi.org/10.3390/cells12040602

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