Repurposing Atovaquone as a Therapeutic against Acute Myeloid Leukemia (AML): Combination with Conventional Chemotherapy Is Feasible and Well Tolerated

SIMPLE SUMMARY: Novel well-tolerated agents are urgently needed to improve outcomes for children with acute myeloid leukemia. Atovaquone is an anti-infective agent which can be used to prevent and treat a type of pneumonia that all children with acute myeloid leukemia require prophylaxis against. In...

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Detalles Bibliográficos
Autores principales: Stevens, Alexandra McLean, Schafer, Eric S., Li, Minhua, Terrell, Maci, Rashid, Raushan, Paek, Hana, Bernhardt, Melanie B., Weisnicht, Allison, Smith, Wesley T., Keogh, Noah J., Alozie, Michelle C., Oviedo, Hailey H., Gonzalez, Alan K., Ilangovan, Tamilini, Mangubat-Medina, Alicia, Wang, Haopei, Jo, Eunji, Rabik, Cara A., Bocchini, Claire, Hilsenbeck, Susan, Ball, Zachary T., Cooper, Todd M., Redell, Michele S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954468/
https://www.ncbi.nlm.nih.gov/pubmed/36831684
http://dx.doi.org/10.3390/cancers15041344

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