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Evaluation of the EPR Effect in the CAM-Model by Molecular Imaging with MRI and PET Using (89)Zr-Labeled HSA

SIMPLE SUMMARY: The CAM model is a promising alternative to murine models in terms of the 3Rs principles. However, its value for the noninvasive assessment of the biodistribution and accumulation of radiolabeled macromolecules by PET and MR imaging needs further evaluation. Thus, we analyzed the bio...

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Detalles Bibliográficos
Autores principales: Hilbrig, Colmar, Löffler, Jessica, Fischer, Gabriel, Scheidhauer, Ellen, Solbach, Christoph, Huber-Lang, Markus, Beer, Ambros J., Rasche, Volker, Winter, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954539/
https://www.ncbi.nlm.nih.gov/pubmed/36831469
http://dx.doi.org/10.3390/cancers15041126