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Embryoid Body Cells from Human Embryonic Stem Cells Overexpressing Dopaminergic Transcription Factors Survive and Initiate Neurogenesis via Neural Rosettes in the Substantia Nigra
Transplantation of immature dopaminergic neurons or neural precursors derived from embryonic stem cells (ESCs) into the substantia nigra pars compacta (SNpc) is a potential therapeutic approach for functional restitution of the nigrostriatal pathway in Parkinson’s disease (PD). However, further stud...
Autores principales: | Ramos-Acevedo, Rodrigo, Morato-Torres, Carmen Alejandra, Padilla-Godínez, Francisco J., Bernal-Conde, Luis Daniel, Palomero-Rivero, Marcela, Zafar, Faria, Collazo-Navarrete, Omar, Soto-Rojas, Luis O., Schüle, Birgitt, Guerra-Crespo, Magdalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954545/ https://www.ncbi.nlm.nih.gov/pubmed/36831872 http://dx.doi.org/10.3390/brainsci13020329 |
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