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Embryoid Body Cells from Human Embryonic Stem Cells Overexpressing Dopaminergic Transcription Factors Survive and Initiate Neurogenesis via Neural Rosettes in the Substantia Nigra

Transplantation of immature dopaminergic neurons or neural precursors derived from embryonic stem cells (ESCs) into the substantia nigra pars compacta (SNpc) is a potential therapeutic approach for functional restitution of the nigrostriatal pathway in Parkinson’s disease (PD). However, further stud...

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Detalles Bibliográficos
Autores principales: Ramos-Acevedo, Rodrigo, Morato-Torres, Carmen Alejandra, Padilla-Godínez, Francisco J., Bernal-Conde, Luis Daniel, Palomero-Rivero, Marcela, Zafar, Faria, Collazo-Navarrete, Omar, Soto-Rojas, Luis O., Schüle, Birgitt, Guerra-Crespo, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954545/
https://www.ncbi.nlm.nih.gov/pubmed/36831872
http://dx.doi.org/10.3390/brainsci13020329

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