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The Receptor for Advanced Glycation Endproducts (RAGE) and Its Ligands S100A8/A9 and High Mobility Group Box Protein 1 (HMGB1) Are Key Regulators of Myeloid-Derived Suppressor Cells

SIMPLE SUMMARY: Cancer immunotherapies using antibodies and genetically modified T cells are effective in a subset of cancer patients. However, many cancer patients do not respond to immunotherapy because their cancers induce cells called myeloid-derived suppressor cells (MDSCs) that antagonize the...

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Detalles Bibliográficos
Autores principales:	Ostrand-Rosenberg, Suzanne, Huecksteadt, Tom, Sanders, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954573/ https://www.ncbi.nlm.nih.gov/pubmed/36831371 http://dx.doi.org/10.3390/cancers15041026

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