Cargando…

Potential Impact of PI3K-AKT Signaling Pathway Genes, KLF-14, MDM4, miRNAs 27a, miRNA-196a Genetic Alterations in the Predisposition and Progression of Breast Cancer Patients

SIMPLE SUMMARY: The genomic landscape of breast cancer (BC) is complex. Previous research studies have not extensively elucidated the correlation of genotypes and allele variations of the PI3K, AKT-1, KLF-14, MDM4 and miRNAs 27a, miR-196a genes with the predisposition of Breast cancer in Saudi Arabi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alzahrani, Othman R., Mir, Rashid, Alatwi, Hanan E., Hawsawi, Yousef M., Alharbi, Amnah A., Alessa, Abdulrahman H., Albalawi, Elham Saleh, Elfaki, Imadeldin, Alalawi, Yousef, Moharam, Laila, El-Ghaiesh, Sabah H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954638/ https://www.ncbi.nlm.nih.gov/pubmed/36831624 http://dx.doi.org/10.3390/cancers15041281

Ejemplares similares

Genetic Determinants of Cardiovascular Disease: The Endothelial Nitric Oxide Synthase 3 (eNOS3), Krüppel-Like Factor-14 (KLF-14), Methylenetetrahydrofolate Reductase (MTHFR), MiRNAs27a and Their Association with the Predisposition and Susceptibility to Coronary Artery Disease
por: Mir, Rashid, et al.
Publicado: (2022)

Comprehensive Molecular Evaluation of HNF-1 Alpha, miR-27a, and miR-146 Gene Variants and Their Link with Predisposition and Progression in Type 2 Diabetes Patients
por: Mir, Rashid, et al.
Publicado: (2023)

Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function
por: Prud'homme, Gerald J., et al.
Publicado: (2016)

Identification and Characterization of Novel Mutations in Chronic Kidney Disease (CKD) and Autosomal Dominant Polycystic Kidney Disease (ADPKD) in Saudi Subjects by Whole-Exome Sequencing
por: Alzahrani, Othman R., et al.
Publicado: (2022)

circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046
por: Zhang, Yue, et al.
Publicado: (2022)

miRModuleNet: Detecting miRNA-mRNA Regulatory Modules
por: Yousef, Malik, et al.
Publicado: (2022)

Role of Selected miRNAs as Diagnostic and Prognostic Biomarkers in Cardiovascular Diseases, Including Coronary Artery Disease, Myocardial Infarction and Atherosclerosis
por: Mir, Rashid, et al.
Publicado: (2021)

Association of miRNA-146a rs2910164 and miRNA-196 rs11614913 polymorphisms in patients with ulcerative colitis: A meta-analysis and review
por: Li, Zhongyi, et al.
Publicado: (2018)

miRNA in Prostate Cancer: New Prospects for Old Challenges
por: Mekhail, Samy M, et al.
Publicado: (2014)

Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse
por: Rudra, Pratyaydipta, et al.
Publicado: (2018)

Association of miR-196a-2 and miR-499 variants with ulcerative colitis and their correlation with expression of respective miRNAs
por: Ranjha, Raju, et al.
Publicado: (2017)

Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions
por: Guo, Li, et al.
Publicado: (2014)

Association of Three Polymorphisms rs11614913, rs2910146, and rs3746444 in miRNA-196a2, miRNA-146a, and miRNA-499 with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
por: Liu, Ying, et al.
Publicado: (2018)

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer
por: Qin, Xin, et al.
Publicado: (2015)

miRNA-576 Alleviates the Malignant Progression of Atherosclerosis through Downregulating KLF5
por: Wang, Jing, et al.
Publicado: (2021)

Correction: Association of miR-196a-2 and miR-499 variants with ulcerative colitis and their correlation with expression of respective miRNAs
por: Ranjha, Raju, et al.
Publicado: (2017)

The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients
por: Fantini, Sebastian, et al.
Publicado: (2016)

rs11614913 polymorphism in miRNA-196a2 and cancer risk: an updated meta-analysis
por: Liu, Yuhan, et al.
Publicado: (2018)

Polymorphisms in miRNAs Gene (146a, 149, 196a) and Susceptibility to ARV-associated Hepatotoxicity
por: Singh, Hari Om, et al.
Publicado: (2019)

miRNAs Copy Number Variations Repertoire as Hallmark Indicator of Cancer Species Predisposition
por: Vischioni, Chiara, et al.
Publicado: (2022)

Using miRNA-Analyzer for the Analysis of miRNA Data
por: Guzzi, Pietro Hiram, et al.
Publicado: (2016)

MiRNAs and miRNA Polymorphisms Modify Drug Response
por: Li, Mu-Peng, et al.
Publicado: (2016)

Deciphering miRNAs’ Action through miRNA Editing
por: Correia de Sousa, Marta, et al.
Publicado: (2019)

Global profiling of miRNAs and the hairpin precursors: insights into miRNA processing and novel miRNA discovery
por: Li, Na, et al.
Publicado: (2013)

Gold Nanoconjugates for miRNA Modulation in Cancer Therapy: From miRNA Silencing to miRNA Mimics
por: Sousa, Diana P., et al.
Publicado: (2022)

Cardio-miRNAs and onco-miRNAs: circulating miRNA-based diagnostics for non-cancerous and cancerous diseases
por: Katoh, Masaru
Publicado: (2014)

Are miRNA-103, miRNA-107 and miRNA-122 Involved in the Prevention of Liver Steatosis Induced by Resveratrol?
por: Gracia, Ana, et al.
Publicado: (2017)

MicroRNAs signatures, bioinformatics analysis of miRNAs, miRNA mimics and antagonists, and miRNA therapeutics in osteosarcoma
por: Otoukesh, Babak, et al.
Publicado: (2020)

Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures
por: Duttagupta, Radha, et al.
Publicado: (2011)

Introns of plant pri-miRNAs enhance miRNA biogenesis
por: Bielewicz, Dawid, et al.
Publicado: (2013)

Regulation of miRNA-mediated gene silencing by miRNA precursors
por: Roy-Chaudhuri, Biswajoy, et al.
Publicado: (2014)

Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts
por: Yang, Fengming, et al.
Publicado: (2017)

Potential miRNAs for miRNA-Based Therapeutics in Breast Cancer
por: Wong, Jun Sheng, et al.
Publicado: (2020)

Generation of MiRNA sponge constructs targeting multiple MiRNAs
por: Jie, Junjin, et al.
Publicado: (2022)

Clinical significance of the expression of miRNA-21, miRNA-31 and miRNA-let7 in patients with lung cancer
por: Wang, Sheng, et al.
Publicado: (2019)

Upregulation of the miRNA-155, miRNA-210, and miRNA-20b in psoriasis patients and their relation to IL-17
por: El-Komy, Mohamed, et al.
Publicado: (2020)

Evaluation of miRNA-7, miRNA-10 and miRNA-21 as diagnostic non-invasive biomarkers of hepatocellular carcinoma
por: Elabd, Walaa K., et al.
Publicado: (2023)

Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4
por: Hartmann, Petra, et al.
Publicado: (2016)

MYOD1 inhibits avian adipocyte differentiation via miRNA-206/KLF4 axis
por: Wang, Zheng, et al.
Publicado: (2021)

Differential Expression of Serum Proinflammatory Cytokine TNF-α and Genetic Determinants of TNF-α, CYP2C19*17, miR-423 Genes and Their Effect on Coronary Artery Disease Predisposition and Progression
por: Almassabi, Rehab F., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4tffulrbfqts9vafbk3483r2m9