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Molecular Insight into Drug Resistance Mechanism Conferred by Aberrant PIK3CD Splice Variant in African American Prostate Cancer

SIMPLE SUMMARY: Higher incidence and mortality rates were observed in African American vs. European American prostate cancers. Alternative mRNA splicing has been suggested as an oncogenic driver in aggressive cancers as well as cancer disparities. Herein, we show that aberrant PIK3CD-S splice varian...

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Detalles Bibliográficos
Autores principales: Ha, Siyoung, Wang, Bi-Dar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954641/
https://www.ncbi.nlm.nih.gov/pubmed/36831678
http://dx.doi.org/10.3390/cancers15041337