An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids

A multitude of in vitro models based on induced pluripotent stem cell (iPSC)-derived motor neurons (MNs) have been developed to investigate the underlying causes of selective MN degeneration in motor neuron diseases (MNDs). For instance, spheroids are simple 3D models that have the potential to be g...

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Detalles Bibliográficos
Autores principales: Castellanos-Montiel, María José, Chaineau, Mathilde, Franco-Flores, Anna Kristyna, Haghi, Ghazal, Carrillo-Valenzuela, Dulce, Reintsch, Wolfgang E., Chen, Carol X.-Q., Durcan, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954647/
https://www.ncbi.nlm.nih.gov/pubmed/36831212
http://dx.doi.org/10.3390/cells12040545

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