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Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation †

Tumor-to-tumor metastasis is a rare event which it is specifically up to pathologists to bring to light correctly. The histological identification of such tumor-to-tumor cases is simple when the respective histologies are different but can be problematic if the case includes two carcinomas with simi...

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Autores principales: Manini, Claudia, Provenza, Claudia, Andrés, Leire, Imaz, Igone, Guarch, Rosa, Nunziata, Raffaelle, López, José I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954947/
https://www.ncbi.nlm.nih.gov/pubmed/36826168
http://dx.doi.org/10.3390/clinpract13010026
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author Manini, Claudia
Provenza, Claudia
Andrés, Leire
Imaz, Igone
Guarch, Rosa
Nunziata, Raffaelle
López, José I.
author_facet Manini, Claudia
Provenza, Claudia
Andrés, Leire
Imaz, Igone
Guarch, Rosa
Nunziata, Raffaelle
López, José I.
author_sort Manini, Claudia
collection PubMed
description Tumor-to-tumor metastasis is a rare event which it is specifically up to pathologists to bring to light correctly. The histological identification of such tumor-to-tumor cases is simple when the respective histologies are different but can be problematic if the case includes two carcinomas with similar cytoarchitecture viewed one inside the other under the microscope. We report four cases of this condition in which clear cell renal cell carcinoma is involved, either as a receptor or as a donor, and remark on the difficulties in recognizing some of them. Appropriate clinical–pathological correlation, including a review of the patient’s antecedents and radiological exams, would be a great help in routinely identifying tumor-to-tumor metastases.
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spelling pubmed-99549472023-02-25 Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation † Manini, Claudia Provenza, Claudia Andrés, Leire Imaz, Igone Guarch, Rosa Nunziata, Raffaelle López, José I. Clin Pract Case Report Tumor-to-tumor metastasis is a rare event which it is specifically up to pathologists to bring to light correctly. The histological identification of such tumor-to-tumor cases is simple when the respective histologies are different but can be problematic if the case includes two carcinomas with similar cytoarchitecture viewed one inside the other under the microscope. We report four cases of this condition in which clear cell renal cell carcinoma is involved, either as a receptor or as a donor, and remark on the difficulties in recognizing some of them. Appropriate clinical–pathological correlation, including a review of the patient’s antecedents and radiological exams, would be a great help in routinely identifying tumor-to-tumor metastases. MDPI 2023-02-16 /pmc/articles/PMC9954947/ /pubmed/36826168 http://dx.doi.org/10.3390/clinpract13010026 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Manini, Claudia
Provenza, Claudia
Andrés, Leire
Imaz, Igone
Guarch, Rosa
Nunziata, Raffaelle
López, José I.
Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation †
title Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation †
title_full Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation †
title_fullStr Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation †
title_full_unstemmed Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation †
title_short Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation †
title_sort tumor-to-tumor metastases involving clear cell renal cell carcinomas: a diagnostic challenge for pathologists needing clinical correlation †
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954947/
https://www.ncbi.nlm.nih.gov/pubmed/36826168
http://dx.doi.org/10.3390/clinpract13010026
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