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Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database

(1) It might be implied that those with Fetal Alcohol Spectrum Disorder (FASD) with fewer sentinel facial features have a “milder” neuropsychological presentation, or present with fewer impairments than those with more sentinel facial features. The aim of this service evaluation was to compare the n...

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Autores principales: Webster, Bethany M., Carlisle, Alexandra C. S., Livesey, Alexandra C., Deeprose, Lucy R., Cook, Penny A., Mukherjee, Raja A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955101/
https://www.ncbi.nlm.nih.gov/pubmed/36832394
http://dx.doi.org/10.3390/children10020266
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author Webster, Bethany M.
Carlisle, Alexandra C. S.
Livesey, Alexandra C.
Deeprose, Lucy R.
Cook, Penny A.
Mukherjee, Raja A. S.
author_facet Webster, Bethany M.
Carlisle, Alexandra C. S.
Livesey, Alexandra C.
Deeprose, Lucy R.
Cook, Penny A.
Mukherjee, Raja A. S.
author_sort Webster, Bethany M.
collection PubMed
description (1) It might be implied that those with Fetal Alcohol Spectrum Disorder (FASD) with fewer sentinel facial features have a “milder” neuropsychological presentation, or present with fewer impairments than those with more sentinel facial features. The aim of this service evaluation was to compare the neuropsychological profile of people with FASD with varying numbers of sentinel facial features. (2) A clinical sample of 150 individuals with FASD, aged between 6 and 37 years, completed various standardised assessments as part of their diagnostic profiling. These included the documented level of risk of prenatal alcohol exposure (4-Digit Diagnostic Code), sensory needs (Short Sensory Profile), cognition (Wechsler Intelligence Scale for Children—4th Edition; WISC-IV), and communication and socialisation adaptive behaviours (Vineland Adaptive Behavior Scale—2nd Edition; VABS-II). As FASD has high comorbidity rates of Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD), these were also reviewed. The profiles of the ‘FASD with 2 or 3 sentinel facial features’ group (n = 41; 28 male, 13 female) were compared with the ‘FASD with 0 or 1 sentinel facial features’ group (n = 109; 50 male, 59 female) using Chi² tests, independent sample t-tests, and Mann-Whitney U analyses (where appropriate). (3) There were no significant differences between the two comparison groups across any measure included in this service evaluation. (4) Whilst sentinel facial features remain an important aspect in recognising FASD, our service evaluation indicates that there is no significant relationship between the number of sentinel facial features and the neuropsychological profile of people with FASD in terms of severity of presentation.
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spelling pubmed-99551012023-02-25 Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database Webster, Bethany M. Carlisle, Alexandra C. S. Livesey, Alexandra C. Deeprose, Lucy R. Cook, Penny A. Mukherjee, Raja A. S. Children (Basel) Article (1) It might be implied that those with Fetal Alcohol Spectrum Disorder (FASD) with fewer sentinel facial features have a “milder” neuropsychological presentation, or present with fewer impairments than those with more sentinel facial features. The aim of this service evaluation was to compare the neuropsychological profile of people with FASD with varying numbers of sentinel facial features. (2) A clinical sample of 150 individuals with FASD, aged between 6 and 37 years, completed various standardised assessments as part of their diagnostic profiling. These included the documented level of risk of prenatal alcohol exposure (4-Digit Diagnostic Code), sensory needs (Short Sensory Profile), cognition (Wechsler Intelligence Scale for Children—4th Edition; WISC-IV), and communication and socialisation adaptive behaviours (Vineland Adaptive Behavior Scale—2nd Edition; VABS-II). As FASD has high comorbidity rates of Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD), these were also reviewed. The profiles of the ‘FASD with 2 or 3 sentinel facial features’ group (n = 41; 28 male, 13 female) were compared with the ‘FASD with 0 or 1 sentinel facial features’ group (n = 109; 50 male, 59 female) using Chi² tests, independent sample t-tests, and Mann-Whitney U analyses (where appropriate). (3) There were no significant differences between the two comparison groups across any measure included in this service evaluation. (4) Whilst sentinel facial features remain an important aspect in recognising FASD, our service evaluation indicates that there is no significant relationship between the number of sentinel facial features and the neuropsychological profile of people with FASD in terms of severity of presentation. MDPI 2023-01-31 /pmc/articles/PMC9955101/ /pubmed/36832394 http://dx.doi.org/10.3390/children10020266 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Webster, Bethany M.
Carlisle, Alexandra C. S.
Livesey, Alexandra C.
Deeprose, Lucy R.
Cook, Penny A.
Mukherjee, Raja A. S.
Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database
title Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database
title_full Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database
title_fullStr Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database
title_full_unstemmed Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database
title_short Evaluating the Difference in Neuropsychological Profiles of Individuals with FASD Based on the Number of Sentinel Facial Features: A Service Evaluation of the FASD UK National Clinic Database
title_sort evaluating the difference in neuropsychological profiles of individuals with fasd based on the number of sentinel facial features: a service evaluation of the fasd uk national clinic database
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955101/
https://www.ncbi.nlm.nih.gov/pubmed/36832394
http://dx.doi.org/10.3390/children10020266
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